Get ready to tantalize your taste buds with this irresistible Cheesy Cajun Garlic Chicken Rotini Skillet! This one-pan wonder combines the bold flavors of Cajun seasoning, creamy garlic, and melted cheeses for a satisfying and comforting dish that’s sure to become a new family favorite.
Table of Contents
What is Cajun Cuisine?
Cajun cuisine has its roots in the culinary traditions of the Acadians, a French-speaking group who were exiled from Canada’s Maritime provinces in the 18th century and eventually settled in the bayous of Louisiana. This unique regional cooking style is known for its use of bold spices, rich sauces, and hearty, stick-to-your-ribs dishes. At the heart of Cajun flavor is a blend of aromatic ingredients like onions, bell peppers, and celery, often referred to as the “holy trinity.” Combined with spices like paprika, cayenne, and garlic, these flavors create a signature Cajun taste that’s both complex and utterly delicious.
Ingredients for Cheesy Cajun Garlic Chicken Rotini Skillet
To bring this Cheesy Cajun Garlic Chicken Rotini Skillet to life, you’ll need a handful of simple ingredients:
- 2 boneless, skinless chicken breasts, cut into bite-sized chunks
- 12 oz rotini pasta
- 2 tbsp olive oil
- 2 tbsp Cajun seasoning
- 1 tsp garlic powder
- 1/2 tsp onion powder
- Salt and pepper to taste
- 4 cloves garlic, minced
- 1 tbsp butter
- 1 cup heavy cream
- 1/2 cup chicken broth
- 1 cup shredded mozzarella cheese
- 1/2 cup grated Parmesan cheese
- 1/2 cup shredded cheddar cheese
- Fresh parsley, chopped (for garnish)
Step-by-Step Instructions
Ready to get cooking? Here’s how to make this Cheesy Cajun Garlic Chicken Rotini Skillet:
- Bring a large pot of salted water to a boil. Cook the rotini pasta according to the package directions until al dente. Drain and set aside.
- In a large skillet, heat the olive oil over medium-high heat. Toss the chicken pieces with the Cajun seasoning, garlic powder, onion powder, salt, and pepper.
- Add the seasoned chicken to the skillet and cook until browned and fully cooked, about 6-7 minutes. Remove the chicken from the skillet and set it aside.
- In the same skillet, melt the butter. Add the minced garlic and sauté for 1 minute until fragrant.
- Stir in the chicken broth and heavy cream, then bring the mixture to a simmer.
- Add the mozzarella, Parmesan, and cheddar cheeses. Stir until the sauce is smooth and creamy.
- Add the cooked rotini and the sautéed chicken back into the skillet. Toss everything together until well-coated in the cheesy Cajun garlic sauce. Let it simmer for 2-3 minutes to allow the flavors to blend.
- Garnish the Cheesy Cajun Garlic Chicken Rotini Skillet with fresh chopped parsley and serve hot, with extra cheese on top if desired.

Tips for Perfecting Your Dish
To ensure your Cheesy Cajun Garlic Chicken Rotini Skillet turns out absolutely amazing, keep these tips in mind:
- Use a good quality Cajun seasoning blend to get the best flavor profile.
- Don’t overcook the pasta – aim for al dente to prevent it from getting mushy.
- Adjust the amount of Cajun seasoning to your desired level of spiciness.
- Shred the cheeses just before adding them to the skillet for optimal melting.
- Let the dish simmer for a few minutes at the end to allow the flavors to meld together.
Serving Suggestions
This Cheesy Cajun Garlic Chicken Rotini Skillet is a complete meal on its own, but you can also serve it with a fresh green salad or some crusty garlic bread for a heartier meal. For a pop of color and texture, top it with chopped green onions, diced tomatoes, or crispy bacon bits.
Nutritional Information
One serving of this Cheesy Cajun Garlic Chicken Rotini Skillet contains approximately 560 calories, 35g of fat, 35g of carbohydrates, and 35g of protein. It’s a satisfying and comforting dish that can be enjoyed as part of a balanced diet.
FAQs about Cheesy Cajun Garlic Chicken Rotini Skillet
1. What ingredients do I need to make Cheesy Cajun Garlic Chicken Rotini Skillet?
To make Cheesy Cajun Garlic Chicken Rotini Skillet, you will need rotini pasta, chicken breast (diced), Cajun seasoning, garlic, onion, bell peppers, cream cheese, shredded cheese (like cheddar or mozzarella), chicken broth, and optional garnishes like parsley or green onions.
2. How long does it take to prepare and cook this dish?
The total time to prepare and cook Cheesy Cajun Garlic Chicken Rotini Skillet is approximately 30-40 minutes. This includes around 10 minutes for preparation and 20-30 minutes for cooking.
3. Can I make this dish ahead of time?
Yes, you can make Cheesy Cajun Garlic Chicken Rotini Skillet ahead of time. Store it in an airtight container in the refrigerator for up to 3 days. To reheat, warm it in a skillet over medium heat, adding a splash of chicken broth or water if it seems dry.
4. Is it possible to make this dish vegetarian or modify it for dietary restrictions?
Absolutely! To make a vegetarian version, you can substitute the chicken with vegetables like mushrooms, zucchini, or a plant-based protein. You can also use gluten-free rotini if you’re avoiding gluten, and adjust the cheese to a dairy-free option if needed.
More Related Recipes You Might Enjoy
- Five-Ingredient Creamy Cajun Chicken Pasta
- Marry Me Bacon Ranch Chicken Skillet
- Loaded BBQ Chicken Mac and Cheese
- Buffalo Chicken Mac and Cheese Skillet
Conclusion
Prepare to be blown away by the incredible flavors of this Cheesy Cajun Garlic Chicken Rotini Skillet! With its perfect balance of spicy, creamy, and cheesy goodness, this one-pan wonder is sure to become a new family favorite. Dig in and enjoy every bite of this irresistible Cajun-inspired dish!
Craving even more magical meals? Browse Amelia’s Pinterest boards for quick dinners, cozy bakes, and tons of flavorful inspiration.
Print
Whip Up This Cheesy Cajun Garlic Chicken Rotini Skillet Today!
- Total Time: 30
- Yield: 4 1x
Description
Get ready to tantalize your taste buds with this irresistible Cheesy Cajun Garlic Chicken Rotini Skillet! This one-pan wonder combines the bold flavors of Cajun seasoning, creamy garlic, and melted cheeses for a satisfying and comforting dish that’s sure to become a new family favorite.
Ingredients
- 2 boneless, skinless chicken breasts, cut into bite-sized chunks
- 12 oz rotini pasta
- 2 tbsp olive oil
- 2 tbsp Cajun seasoning
- 1 tsp garlic powder
- 1/2 tsp onion powder
- Salt and pepper to taste
- 4 cloves garlic, minced
- 1 tbsp butter
- 1 cup heavy cream
- 1/2 cup chicken broth
- 1 cup shredded mozzarella cheese
- 1/2 cup grated Parmesan cheese
- 1/2 cup shredded cheddar cheese
- Fresh parsley, chopped (for garnish)
Instructions
1. Bring a large pot of salted water to a boil. Cook the rotini pasta according to the package directions until al dente. Drain and set aside.
2. In a large skillet, heat the olive oil over medium-high heat. Toss the chicken pieces with the Cajun seasoning, garlic powder, onion powder, salt, and pepper.
3. Add the seasoned chicken to the skillet and cook until browned and fully cooked, about 6-7 minutes. Remove the chicken from the skillet and set it aside.
4. In the same skillet, melt the butter. Add the minced garlic and sauté for 1 minute until fragrant.
5. Stir in the chicken broth and heavy cream, then bring the mixture to a simmer.
6. Add the mozzarella, Parmesan, and cheddar cheeses. Stir until the sauce is smooth and creamy.
7. Add the cooked rotini and the sautéed chicken back into the skillet. Toss everything together until well-coated in the cheesy Cajun garlic sauce. Let it simmer for 2-3 minutes to allow the flavors to blend.
8. Garnish the Cheesy Cajun Garlic Chicken Rotini Skillet with fresh chopped parsley and serve hot, with extra cheese on top if desired.
Notes
Use a good quality Cajun seasoning blend to get the best flavor profile.
Don’t overcook the pasta – aim for al dente to prevent it from getting mushy.
Adjust the amount of Cajun seasoning to your desired level of spiciness.
Shred the cheeses just before adding them to the skillet for optimal melting.
Let the dish simmer for a few minutes at the end to allow the flavors to meld together.
- Prep Time: 10
- Cook Time: 20
- Category: Dinner
- Method: Stovetop
- Cuisine: Cajun, Chicken, Pasta, Skillet
Nutrition
- Serving Size: 560
- Calories: 2
- Sugar: 800
- Sodium: 35
- Fat: 20
- Saturated Fat: 10
- Unsaturated Fat: 0
- Trans Fat: 120
- Carbohydrates: 3
- Fiber: 35
- Protein: undefined
- Cholesterol: 35